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Jiaxin, Yu; Gu, Zhouyu; Wang, Lichan; Zhang, Qian; Pu, Yumei; Hu, Qingang; Xia, Chengwan; Wang, Yuxin, 2024, "Replication Data for: Three-dimensional Measurement of the Depth of Invasion in Oral Squamous Cell Carcinoma Samples using Lugol’s Iodine-enhanced Micro-computed Tomography: An Original Study", https://doi.org/10.48331/scielodata.4NM6WS, SciELO Data, V1
Objectives: Depth of invasion (DOI) in oral squamous cell carcinoma (OSCC) guides treatment and prognosis but lacks three-dimensional (3D) insight. Thus, this study aimed to investigate the feasibility and accuracy of using Lugol’s iodine-enhanced micro-computed tomography (CT) f... |
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Lugol's iodine-enhanced micro-CT three-dimensional measurement DOI research flow chart
The in vitro OSCC samples were fully soaked in freshly prepared 3% Lugol's iodine for 12 hours. Subsequently, the samples were scanned using micro-CT. After scanning, the samples were digitall... |
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Measuring the depth of invasion from the deepest point of invasion reconstructed basement membrane line.
The black two-way arrow solid line represents the depth of invasion (DOI).The dashed line represents the tumor boundary.
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Lugol's iodine-enhanced micro-computed tomography and pathological images of oral squamous cell carcinoma in vitro sample. The dashed line represents the tumor boundary. The black boxes correspond to the enlarged parts of the local tissue in the (C) and (D) figures. |
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Lugol’s iodine-enhanced micro-computed tomography (CT) can identify minimal residual lesions. The dashed line represents the tumor boundary
(A) The tumor is outlined by a dotted line. (B) Magnification of tumor site on micro-CT. (C) Pathological image of the same section. (D) Ma... |
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Depth of invasion (DOI) could be measured accurately by Lugol’s iodine-enhanced three-dimensional micro-CT imaging. The dashed line represents the tumor boundary. Double arrows with solid black lines indicate DOI.
(A) 3D micro-computed tomography (CT) image (the red region was t... |
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Correlation between p-depth of invasion (DOI) and r-DOI |
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Patients’ characteristics and the change of T-stage |
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Characteristics of patients and voxel value of tissues |
