651 to 660 of 5,399 Results
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MD5: f90be0a594d0b2c8498d11115956d605
MTT viability assay to determine the toxicity of Dynasore in HGFs (A). (B) ZOL-induced viability loss rescue assay where UN indicates untreated (set to 100% viability) and the microM Dynasore concentrations are designated as Dyn 10, Dyn 30, etc. and ZOL is 50 microM in concentrat... |
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MD5: 38ff2dbcf169524a0ac3ae289a7d7a82
Confocal fluorescence microscopy to determine whether dextran and ZOL colocalize in HGFs. From the same experiment, a representative photomicrograph of an HGF in the absence of Dynasore (A, C, E, and G) and a representative photomicrograph of an HGF in the presence of Dynasore (B... |
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MD5: 1848dacb3313d0438b270a286ed930bd
Confocal fluorescence microscopy of live HGFs exposed to LysoSensor Green DND-189 to measure endosomal acidification. Representative field of HGFs in the absence (A) and presence (B) of 30 microM Dynasore in which the exposure settings were kept constant. 20X objective, scale bar... |
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MD5: a264a0113bfaeea8a79565c42aabc60d
Measurement of the perinuclear localization of ZOL and the positive control for macropinocytosis, dextran, in the absence and presence of 30 microM Dynasore. Violin plots display the HGF perinuclear proportion of intracellular TRITC-dextran (A) and AF647-ZOL (D) fluorescence. Hor... |
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MD5: 496fd3da516f74ba23d636c4a2e04675
Text summary and data displaying the major findings. |
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MD5: db50edfaef672c4413910622875fe627
This graph displays the "data not shown" in the Dynasore rescue portion of Results. An optimized dose of imipramine (IMI) of 25 microM for one hour prior to 72 hours of incubation in the presence of zoledronate does not rescue the 50 microM zoledronate (ZOL)-treated HGFs. Error b... |
Tabular Data - 1.9 KB - 11 Variables, 25 Observations - UNF:6:cShYK+KhoIAqGIBEkEIfQQ==
This file contains the data used to make the graph that was "data not shown" in the Dynasore rescue portion of Results. The graph is the file entitled "HGFIMIRescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that an optimized dose of imipramine (IMI)... |
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MD5: d3c779177990d91baf6a82fa93ff3a1e
This graph shows that optimized doses of phosphonoformic acid (PFA) from 0.25-0.75 mM for either a one-hour pre-treatment (PRE) prior or continual exposure during 72 hours of incubation in the presence of zoledronate do not rescue the 50 microM zoledronate (ZOL)-treated human cal... |
Tabular Data - 1.8 KB - 17 Variables, 13 Observations - UNF:6:Tt8WyaVO2OzMPxxG+C8knQ==
This file contains the data used to make the graph that was part of the "data not shown" in the PFA rescue portion of Results. The graph is the file entitled "OsteoblastPFARescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that optimized doses of phosp... |
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MD5: 67fae0c673edb167b8ee575b1ea088dc
This graph shows that optimized doses of phosphonoformic acid (PFA) from 0.25-0.75 mM for either a one-hour pre-treatment (PRE) prior or continual exposure during 72 hours of incubation in the presence of zoledronate do not rescue the 50 microM zoledronate (ZOL)-treated RAW264.7,... |
