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JPEG Image - 235.1 KB - MD5: 05895733f3d555d8c070485b09dad92c
AFM images. Legend: µV- microvolt ; 3D topography images (A and C) and 2D amplitude images (B and D). NFW (A and B); NFE (C and D). Scale = 2 µm (micrometer).
JPEG Image - 22.9 KB - MD5: 03efb2518b00bfd1d3287405c3098ffa
Nanoparticle size graph from AFM analysis. Legend: *p<0.0001 after Mann-Whitney test. NFE (Nanostructured formulation containing eugenol); NFW (Nanostructured formulation without eugenol); nm (nanometer).
JPEG Image - 31.4 KB - MD5: 697fe1fe71e16f502a8b9eb42aa32805
In vitro release profile of eugenol encapsulated in nano-structured lipid carriers and free eugenol solution: Legend: *P<0.05 after two-way ANOVA test. NFE (Nanostructured formulation containing eugenol).
JPEG Image - 71.9 KB - MD5: e8fb3e2892051b6537781450b2108e9b
Activity of the test solutions on C. albicans and C. glabata biofilms: Legend: One-way ANOVA and Tukey test: NFE vs. NFW (P˂0.0001); NFE vs. SS(P˂0.0001); NFE vs. FE (P˂0.0001); NFW vs. SS (P˃0.999) NFW vs. FE (P˂0.0001); FE vs. SS (P˂0.0001). NFE (Nanostructured formulation con...
JPEG Image - 3.1 MB - MD5: 120ebe53e93ca0c59942882e55747789
Bmal1 knockout aggravates bone resorption in the periodontitis group. (a) Bone resorption of the maxilla in each group. Three-dimensional (3D) reconstruction and two-dimensional (2D) CT images are shown. (b) Quantitative analysis of the alveolar bone resorption area. (c) Quantita...
JPEG Image - 4.2 MB - MD5: 345dee6cb3d35eea2167baf8f460df1f
Bmal1 knockout increases p65 expression in periodontitis. (a) Immunofluorescence staining of p65 in the maxilla. Green fluorescence shows the expression of p65. (b) Statistical analysis of the integrated density/area of p65-positive cells in (a). (c) Statistical analysis of the p...
JPEG Image - 905.6 KB - MD5: d963da3939fc0940116f8f84f9415764
Bmal1 knockout increases pp65 and p65 expression in LPS-stimulated BMDMs. (a) pp65 and p65 immunofluorescence staining of bone marrow macrophages. White arrows show pp65 and p65-positive cells. (b) Average optical density. (c) Percentage of pp65-positive cells. *p < 0.05, **p < 0...
JPEG Image - 553.4 KB - MD5: 2eb134094da7ec07d28f241b5acde362
Bmal1 knockout affects inflammatory factor expression in periodontitis and LPS-stimulated BMDMs. (a) Expression levels of Il1b, Il6, and Tnfa. (b) mRNA expression of inflammatory cytokines in the bone marrow macrophages of Bmal1-knockout mice. (c) mRNA expression of N1rd1, Nfil3,...
JPEG Image - 1.6 MB - MD5: ecdc2a37b5538746b1ec995327cf6e24
Image of genotyping by DNA gel electrophoresis Bmal1-/- DNA ladder is 600bp, Bmal1+/- DNA ladder is 600bp and 399bp, Bmal1+/+ DNA ladder is 399bp.
JPEG Image - 2.3 MB - MD5: 1c2c4dce1bdbf789c2ab7ffb25cebafd
Image of TRAP stain and characterization of BMDMs. Bmal1 knockout affects osteoclasts in periodontitis and characterization of BMDMs. (a) TRAP staining in the periodontitis lesion tissue in different groups. (b) Quantification of TRAP-positive cells in different groups in “A”. (c...
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