Journal of Applied Oral Science

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441 to 450 of 754 Results

Figure_7.jpg Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse JPEG Image - 587.9 KB - MD5: 9dc1344c4edc0fc13099857f81b29ffa Figure 7. Osteoblastic STAT3 mediated the mechanical loading-increased osteogenesis. A-B, The protein levels of JAK2, pJAK2, STAT3, and pSTAT3. C-D, The protein levels of Runx2, COL-I, Osterix, and ALP. E-F, Alizarin red staining and ALP staining. *P < 0.05
Readme.txt Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse Plain Text - 2.2 KB - MD5: 671ef8f57bb8d88fc2428e77ee65cdef
Supplementary_Figure_1.jpg Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse JPEG Image - 459.5 KB - MD5: 4672504ff0a0e6afaa6adc3543ae6ce4 Supplementary Figure 1. Stattic administration inhibited pSTAT3 expression in MPS region. A, Immunohistochemical staining of pSTAT3. B, Semiquantitative analysis of pSTAT3. *p<0.05
Supplementary_Figure_2.jpg Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse JPEG Image - 150.8 KB - MD5: f6e76660a094bf65e96c56894b5a7f6c Supplementary Figure 2. Preliminary experiment to confirm the effectiveness of Stattic on inhibiting STAT3 phosphorylation
A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants Feb 2, 2023 Ren, Jiabao; Zhao, Ya; Yuan, Yunyun; Zhang, Jing; Ding, Yulin; Li, Meikang; An, Yilin; Chen, Wenjing; Zhang, Li; Liu, Boyu; Zheng, Shushen; Shen, Wenjing, 2023, "A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants", https://doi.org/10.48331/scielodata.OMMQEH, SciELO Data, V1 It has been reported that >91.9% of non-syndromic tooth agenesis cases are caused by seven pathogenic genes. Objective: Here, we report novel heterozygous PAX9 variants in a Chinese family with non-syndromic oligodontia and summarize the reported genotype-phenotype relationship o...
DATASET_README.txt Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants Plain Text - 4.0 KB - MD5: f91be16a67a89c3fd03b178f97c8ae4c
figure_1.jpg Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants JPEG Image - 283.0 KB - MD5: 59f7fb9ea7e86e1e1eab6ec429522cbb Identification of a compound heterozygous PAX9 variant in a Chinese family with non-syndromic oligodontia. (a) The pedigree of the Chinese family. The black arrow indicates the proband. (b) DNA sequencing chromatograms of the family and TA cloning sequencing of the proband showin...
figure_2.jpg Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants JPEG Image - 752.9 KB - MD5: 3b92593bdab77294df5c404898a70e90 Dental characteristics of a Chinese family with non-syndromic oligodontia. a-d: (a) Facial characteristics of the proband; (b-c) Intraoral images; (d) Panoramic radiographs and schematic diagram of missing teeth; (e) Facial characteristics of the proband’s mother; (f-g) Intraoral...
figure_3.jpg Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants JPEG Image - 775.9 KB - MD5: 9feccb072bee36f2ce3eaebbb803c44d Conservation and bioinformatics analysis and structural modeling of PAX9. (a) Schematic diagram of the wild-type PAX9 protein and the localization of the novel compound heterozygous PAX9 variant identified in this study. (b) Conservation analysis of PAX9 amino acid sequences in s...
figure_4.jpg Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants JPEG Image - 91.6 KB - MD5: bf531ed5ad028fb6c27cff26159c49c1 Phenotype composition of the 160 patients reviewed.

Figure_7.jpg

Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse

JPEG Image - 587.9 KB -

Figure 7. Osteoblastic STAT3 mediated the mechanical loading-increased osteogenesis. A-B, The protein levels of JAK2, pJAK2, STAT3, and pSTAT3. C-D, The protein levels of Runx2, COL-I, Osterix, and ALP. E-F, Alizarin red staining and ALP staining. *P < 0.05

Readme.txt

Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse

Plain Text - 2.2 KB -

Supplementary_Figure_1.jpg

Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse

JPEG Image - 459.5 KB -

Supplementary Figure 1. Stattic administration inhibited pSTAT3 expression in MPS region. A, Immunohistochemical staining of pSTAT3. B, Semiquantitative analysis of pSTAT3. *p<0.05

Supplementary_Figure_2.jpg

Mar 28, 2023 - Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse

JPEG Image - 150.8 KB -

Supplementary Figure 2. Preliminary experiment to confirm the effectiveness of Stattic on inhibiting STAT3 phosphorylation

A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

Feb 2, 2023

Ren, Jiabao; Zhao, Ya; Yuan, Yunyun; Zhang, Jing; Ding, Yulin; Li, Meikang; An, Yilin; Chen, Wenjing; Zhang, Li; Liu, Boyu; Zheng, Shushen; Shen, Wenjing, 2023, "A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants", https://doi.org/10.48331/scielodata.OMMQEH, SciELO Data, V1

It has been reported that >91.9% of non-syndromic tooth agenesis cases are caused by seven pathogenic genes. Objective: Here, we report novel heterozygous PAX9 variants in a Chinese family with non-syndromic oligodontia and summarize the reported genotype-phenotype relationship o...

DATASET_README.txt

Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

Plain Text - 4.0 KB -

figure_1.jpg

Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

JPEG Image - 283.0 KB -

Identification of a compound heterozygous PAX9 variant in a Chinese family with non-syndromic oligodontia. (a) The pedigree of the Chinese family. The black arrow indicates the proband. (b) DNA sequencing chromatograms of the family and TA cloning sequencing of the proband showin...

figure_2.jpg

Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

JPEG Image - 752.9 KB -

Dental characteristics of a Chinese family with non-syndromic oligodontia. a-d: (a) Facial characteristics of the proband; (b-c) Intraoral images; (d) Panoramic radiographs and schematic diagram of missing teeth; (e) Facial characteristics of the proband’s mother; (f-g) Intraoral...

figure_3.jpg

Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

JPEG Image - 775.9 KB -

Conservation and bioinformatics analysis and structural modeling of PAX9. (a) Schematic diagram of the wild-type PAX9 protein and the localization of the novel compound heterozygous PAX9 variant identified in this study. (b) Conservation analysis of PAX9 amino acid sequences in s...

figure_4.jpg

Feb 2, 2023 - A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

JPEG Image - 91.6 KB -

Phenotype composition of the 160 patients reviewed.

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