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May 12, 2025 - Journal of Applied Oral Science
Li, Lei; Lin, Haojie; Hu, Shuchang; Sun, Wei; Ji, Wei, 2025, "Replication Data for: Synthetic sticky bone grafts enhance bone regeneration: a preclinical evaluation in rat models", https://doi.org/10.48331/scielodata.4QEI41, SciELO Data, V1
Deproteinized bovine bone minerals (DBBMs) are effective for bone regeneration, however, their limited plasticity can hinder treatment of extensive bone defects. This study aimed to develop a composite bone grafting material that is easy to deploy surgically and promotes robust b...
JPEG Image - 1.6 MB - MD5: 50f68d811fd0bedc4bf958e2fe23b3ca
Figure 1. Preparation and characterization of the synthetic sticky bone (SSB). (a) Schematic illustration of the SSB preparation method, creating an injectable material made of hemostatic gelatin-based colloidal gel and deproteinized bovine bone mineral (DBBM) particles. Note: Th...
JPEG Image - 89.8 KB - MD5: e1eab62df6daac9c7100b22fb73a997b
Figure 2- Schematic flowchart of the experiment. Note: This figure was created with BioRender.com.
JPEG Image - 245.5 KB - MD5: 1972eaaf342d7ca3ba5c97cdbd62da4a
Figure 3- Rat critical-size jawbone defects treated with the SSB, DBBM particles, and gelatin-based colloidal gel (Gel), respectively. Empty defect (blank) was set as negative control.
JPEG Image - 404.8 KB - MD5: 380a89c8667ea9c468e5ea2a2d98b0f9
Figure 4- Microcomputed tomography (μCT) of Rat critical-size jawbone defects treated with the SSB, DBBM at postoperative 2 weeks. (a-b) Representative reconstructions from μCT are shown for the rat critical-size jawbone defect treated with DBBM (a) and SSB (b); green color indic...
JPEG Image - 379.7 KB - MD5: f87b50896fed442d89e46c282c719e10
Figure 5- Microcomputed tomography (μCT) of Rat critical-size jawbone defects treated with the SSB, DBBM at postoperative 4 weeks. (a-b) Representative reconstructions from μCT are shown for the rat critical-size jawbone defect treated with DBBM (a) and SSB (b); green color indic...
JPEG Image - 1.0 MB - MD5: 176ab191d526142443f8964562f1311f
Figure 6- Hematoxylin and Eosin (H&E) Staining of defect samples treated with DBBM or SSB on postoperative 2 weeks and 4 weeks. Black arrows indicated blood vessels. Asterisks indicated newly formed osteoid. Scale bar was 1 mm and 200 m for low and high magnification, respectivel...
JPEG Image - 2.1 MB - MD5: c15094c36db312b096f4942f6c203499
Figure 7- Masson trichrome staining and histomorphometric analysis of defects treated with DBBM and SSB. (a) Representative Masson trichrome staining images of defects with different treatments at postoperative 2 weeks and 4 weeks. White dash line indicates the border of the defe...
JPEG Image - 565.1 KB - MD5: 72c8b3bca1244f189d20c13673689fa5
Supplementary Figure 1. Microcomputed tomography (μCT) of Rat critical-size jawbone defects treated with the gelatin-based colloidal gel, and blank group postoperative 2 and 4 weeks.
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