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Unknown - 13.1 KB - MD5: 1e003f68001791411dac44c47eb88299
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Nov 4, 2022 - Journal of Applied Oral Science
Chaves, Ian; Zicker, Marina Campos; Laranjeira, Alice de Oliveira; Silveira, Ana Letícia Malheiros; Aguiar, Daniele Cristina de; Barrioni, Breno Rocha; Ferreira, Adaliene Versiani de Matos; Teixeira, Mauro Martins; Silva, Tarcília Aparecida da; Souza, Daniele da Glória de; Madeira, Mila Fernandes Moreira, 2022, "Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice", https://doi.org/10.48331/scielodata.OIBYC1, SciELO Data, V1
The current study aimed to relate obesity, changes in oral microbiota, and induction of alveolar bone loss, as seen in PD. Two obesity mice models were performed, one using 12 weeks of the dietary protocol with a high-fat (HF) diet in C57BL/6 mice and the other using leptin recep...
Comma Separated Values - 3.7 KB - MD5: 38ce8c5582689600ff91c65f21ed2eb3
Figure 1- Mice fed HF diet presented body weight gain, increased adiposity, and alteration in the leptin and adiponectin concentrations. A: Weight parameters measured for 12 weeks, once a week, in groups of mice fed with control chow, AIN-93, or HF diet. B: Adiposity index measur...
Comma Separated Values - 234 B - MD5: 29b5e35bab7ef805931017d3fefbca9d
Supplementary figure 1- Analysis of alveolar bone loss of infected (Aa) or sham-infected (C) mice submitted to standard or HF 45% diet. Analysis of alveolar bone loss after 12 weeks with control or HF 45% diet, and 4 weeks after oral inoculation of A. actinomycetemcomitans (Aa)....
Comma Separated Values - 1.3 KB - MD5: 1cf06e392a4d38b2539d562d137a0394
Figure 2- Analysis of periodontal tissues and serum changes in db/db-/- mice. (A) Representative images of alveolar bone loss in WT and db/db-/- mice. (B) Analysis of alveolar bone loss in WT and db/db-/- mice. (C) MPO quantification in periodontal tissues of WT and db/db-/- mice...
Comma Separated Values - 4.2 KB - MD5: fbd53d289477603874c261103c0eaebb
Figure 3- Analysis of periodontal tissues of infected or sham-infected mice subjected to the control or HF diets. (A) Representative images of hemimaxillae of mice from different experimental groups. (B) Analysis of alveolar bone loss after 12 weeks with diet and 4 weeks after or...
Comma Separated Values - 601 B - MD5: d29716e748d69c106cdcc56194a3ca77
Figure 4- Topical application of CHX impairs HF diet-induced alveolar bone loss. (A) Representative images of hemimaxillae of mice from different experimental groups. (B) Alveolar bone loss evaluation after 12 weeks of diet and 4 weeks after CHX treatment. (C) Neutrophil influx....
Comma Separated Values - 920 B - MD5: 7e007906c478befe41346c0ff5e30c62
Figure 5- Micro-CT analysis of maxillae of mice fed with the control (C) or HF (HF) diet, or HF diet plus treatment with CHX. (A) Representative Micro-CT images. Arrows indicate the alveolar bone (B) Bone Mineral Density (BMD). (C) Correlation between bone mineral density and adi...
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