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Figure 1- Mice fed HF diet presented body weight gain, increased adiposity, and alteration in the leptin and adiponectin concentrations. A: Weight parameters measured for 12 weeks, once a week, in groups of mice fed with control chow, AIN-93, or HF diet. B: Adiposity index measur...
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Supplementary figure 1- Analysis of alveolar bone loss of infected (Aa) or sham-infected (C) mice submitted to standard or HF 45% diet. Analysis of alveolar bone loss after 12 weeks with control or HF 45% diet, and 4 weeks after oral inoculation of A. actinomycetemcomitans (Aa)....
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Figure 2- Analysis of periodontal tissues and serum changes in db/db-/- mice. (A) Representative images of alveolar bone loss in WT and db/db-/- mice. (B) Analysis of alveolar bone loss in WT and db/db-/- mice. (C) MPO quantification in periodontal tissues of WT and db/db-/- mice...
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Figure 3- Analysis of periodontal tissues of infected or sham-infected mice subjected to the control or HF diets. (A) Representative images of hemimaxillae of mice from different experimental groups. (B) Analysis of alveolar bone loss after 12 weeks with diet and 4 weeks after or...
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Figure 4- Topical application of CHX impairs HF diet-induced alveolar bone loss. (A) Representative images of hemimaxillae of mice from different experimental groups. (B) Alveolar bone loss evaluation after 12 weeks of diet and 4 weeks after CHX treatment. (C) Neutrophil influx....
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Figure 5- Micro-CT analysis of maxillae of mice fed with the control (C) or HF (HF) diet, or HF diet plus treatment with CHX. (A) Representative Micro-CT images. Arrows indicate the alveolar bone (B) Bone Mineral Density (BMD). (C) Correlation between bone mineral density and adi...
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