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Oct 18, 2023 - Journal of Applied Oral Science
Ev, Laís Daniela; Poloni, Joice Faria; Damé-Teixeira, Nailê; Corralo, Daniela Jorge; Henz, Sandra Liana; Do, Thuy; Maltz, Marisa; Parolo, Clarissa Cavalcanti Fatturi, 2023, "Replication Data for: Biofilm dysbiosis and caries activity: a surface or an individual issue?", https://doi.org/10.48331/scielodata.MT231Y, SciELO Data, V1
This study aimed to analyze the functional profile of supragingival biofilm from sound (CAs), active (CAa), and inactive (CAi) enamel caries lesions from caries-active individuals to provide insights into the diversity of biological processes regarding biofilm dysbiosis. A metatr...
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Variability in microbial composition among conditions (Fig.1a), and patients (Fig.1b) (R factoextra). The PCA plot Fig. 1.a separates samples according to caries status. The PCA plot Fig. 1.b separates samples according to subjects. Fig. 1a: Red represents biofilm samples from ac...
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Euclidean distance plot. Green shades represent patients (patient 1 (P1); patient 2 (P2); patient 3 (P3); patient 4 (P4); and patient 5 (P5)). Purple shades represent tooth surface clinical condition (active non-cavitated surfaces – CAa; arrested non-cavitated surfaces – CAi; and...
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Venn diagram depicting the overlap between the differential expressed genes of the three different biofilm collected tooth surfaces (CAa – non-cavitated caries lesions surfaces; CAi – arrested non-cavitated lesions surfaces; CAs – sound tooth surfaces). Fig 3a represents genes up...
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Heatmap representing all genes up-regulated in one or more conditions and patient origin. Genes are grouped by bioprocess. P1 (patient 1); P2 (patient 2); P3 (patient 3); P4 (patient 4);P5 (patient 5). Conditions: CAa (non-cavitated caries lesions surfaces of caries-active patien...
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Data description
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Supplementary Figure 1. Samples and condition correlations plot. Blue corresponds to a positive correlation, and red corresponds to a negative correlation. CAa correspond to non-cavitated active lesions surfaces (CAa_1; CAa_2; CAa_3; CAa_4; and CAa_5); CAi correspond to non-cavit...
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Supplementary Table 1. Up-regulated genes in CAa in relation to CAi and to CAs
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