SciELO Data

Metrics

12,778 Downloads

Featured Dataverses

In order to use this feature you must have at least one published or linked dataverse.

Publish Dataverse

Are you sure you want to publish your dataverse? Once you do so it must remain published.

Publish Dataverse

This dataverse cannot be published because the dataverse it is in has not been published.

Delete Dataverse

Are you sure you want to delete your dataverse? You cannot undelete this dataverse.

Publication Year: 2023

1,441 to 1,450 of 1,452 Results

Figure_6.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 1007.0 KB - MD5: 09d779f58bb300917e8f61d7dab2e6f5 Figure 6. Effects of C5aR antagonists on NF-κB signaling pathway activation and TLR4 expression in LPS-stimulated HGFs.(A) Effects of C5aR antagonists on mRNA levels of p65, p-p65, IκBα, p-IκBα and TLR4 in LPS-stimulated HGFs.(B) Effects of C5aR antagonists on protein levels of p...
Figure_7.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 4.5 MB - MD5: 419a93b3d9988aea661ba0fb63c17492 Figure 7. The effects of C5aR antagonists on p-p65 translocation into the nucleus were used to detect by immunoflfluorescence staining.(A-C) LPS+C5aR antagonists group.(D-F) The control group.(G-I) LPS group. The Blue staining represented the nucleus; The green staining was p-p65...
Figure_8.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 975.9 KB - MD5: e31d40908889cc5a560522952d4d06e4 Figure 8. Effects of C5aR antagonists on MAPK signal pathway activation in LPS-stimulated HGFs.(A) Effects of C5aR antagonists on mRNA levels of JNK, p-JNK, c-JUN and p-c-JUN in LPS-stimulated HGFs. (B) Effects of C5aR antagonists on protein levels of JNK, p-JNK, c-JUN, and p-c-J...
Figure_S1.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 1.3 MB - MD5: cac855a33823ba41a8249455503be1e1 Figure S1. Effects of LPS and C5aRA on the activity of HGFs using the CCK8 assay. (A) HGFs were treated with LPS at concentrations of 0.1, 1, and 5 μg/mL for 24, 48, and 72 h, respectively. (B) HGFs were treated with C5aRA at concentrations of 0.1, 1, and 5 μg/mL for 24, 48, and...
Figure_S2.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 3.0 MB - MD5: 3d3960b130038f3421d122e3949ed393 Figure S2. Effects of different concentrations of LPS on the expression of C5aR, IL-1β, IL-6, and TNF-α mRNA, determined using RT-PCR analysis. (A) C5aR; (B) IL-6; (C) IL-1β; and (D) TNF-α mRNA expression. Data represent the mean ± SEM of three independent experiments. * P < 0.05...
Figure_S3.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 3.4 MB - MD5: 2663c792229305b8584174eccbf93ebe Figure S3. Effects of different concentrations of C5aRA on the expression of C5aR, IL-1β, IL-6, and TNF-α mRNA, determined using RT-PCR analysis. (A) C5aR; (B) IL-6; (C) IL-1β; and (D) TNF-α mRNA expression. Data represent the mean ± SEM of three independent experiments. * P < 0....
Graphical_Abstract.jpg Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways JPEG Image - 1.2 MB - MD5: 7c6fd5205e5631af918798512bb58073 Schematic diagram of mechanism for anti-inflammatory action of C5aR antagonists (W54011). Complement and Toll-like receptors 4 (TLR4) are co-activated in response to lipopolysaccharide (LPS). During the activation of the complement cascade, C5 may be cleaved into its active produ...
README.txt Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways Plain Text - 3.8 KB - MD5: 24501ebd59c9ae1e9855c1c58c36b01c
Replication Data for: Efetividade do Trastuzumabe adjuvante em mulheres com câncer de mama HER-2+ no SUS Jan 2, 2023 - Ciência & Saúde Coletiva Batista, Joanna d'Arc Lyra; Alves, Rafael José Vargas; Cardoso, Taís Belladona; Moreno, Marcelo; Tiscoski, Katsuki Arima; Polanczyk, Carisi Anne, 2023, "Replication Data for: Efetividade do Trastuzumabe adjuvante em mulheres com câncer de mama HER-2+ no SUS", https://doi.org/10.48331/scielodata.KG1BRG, SciELO Data, V1, UNF:6:twusn2GcEJRPJRyvuyA/9g== [fileUNF] Banco de dados do artigo.
BANCO2022_trastuz.tab Jan 2, 2023 - Replication Data for: Efetividade do Trastuzumabe adjuvante em mulheres com câncer de mama HER-2+ no SUS Tabular Data - 12.8 KB - 24 Variables, 90 Observations - UNF:6:twusn2GcEJRPJRyvuyA/9g==

Figure_6.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 1007.0 KB -

Figure 6. Effects of C5aR antagonists on NF-κB signaling pathway activation and TLR4 expression in LPS-stimulated HGFs.(A) Effects of C5aR antagonists on mRNA levels of p65, p-p65, IκBα, p-IκBα and TLR4 in LPS-stimulated HGFs.(B) Effects of C5aR antagonists on protein levels of p...

Figure_7.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 4.5 MB -

Figure 7. The effects of C5aR antagonists on p-p65 translocation into the nucleus were used to detect by immunoflfluorescence staining.(A-C) LPS+C5aR antagonists group.(D-F) The control group.(G-I) LPS group. The Blue staining represented the nucleus; The green staining was p-p65...

Figure_8.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 975.9 KB -

Figure 8. Effects of C5aR antagonists on MAPK signal pathway activation in LPS-stimulated HGFs.(A) Effects of C5aR antagonists on mRNA levels of JNK, p-JNK, c-JUN and p-c-JUN in LPS-stimulated HGFs. (B) Effects of C5aR antagonists on protein levels of JNK, p-JNK, c-JUN, and p-c-J...

Figure_S1.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 1.3 MB -

Figure S1. Effects of LPS and C5aRA on the activity of HGFs using the CCK8 assay. (A) HGFs were treated with LPS at concentrations of 0.1, 1, and 5 μg/mL for 24, 48, and 72 h, respectively. (B) HGFs were treated with C5aRA at concentrations of 0.1, 1, and 5 μg/mL for 24, 48, and...

Figure_S2.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 3.0 MB -

Figure S2. Effects of different concentrations of LPS on the expression of C5aR, IL-1β, IL-6, and TNF-α mRNA, determined using RT-PCR analysis. (A) C5aR; (B) IL-6; (C) IL-1β; and (D) TNF-α mRNA expression. Data represent the mean ± SEM of three independent experiments. * P < 0.05...

Figure_S3.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 3.4 MB -

Figure S3. Effects of different concentrations of C5aRA on the expression of C5aR, IL-1β, IL-6, and TNF-α mRNA, determined using RT-PCR analysis. (A) C5aR; (B) IL-6; (C) IL-1β; and (D) TNF-α mRNA expression. Data represent the mean ± SEM of three independent experiments. * P < 0....

Graphical_Abstract.jpg

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

JPEG Image - 1.2 MB -

Schematic diagram of mechanism for anti-inflammatory action of C5aR antagonists (W54011). Complement and Toll-like receptors 4 (TLR4) are co-activated in response to lipopolysaccharide (LPS). During the activation of the complement cascade, C5 may be cleaved into its active produ...

README.txt

Jan 2, 2023 - C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

Plain Text - 3.8 KB -

Replication Data for: Efetividade do Trastuzumabe adjuvante em mulheres com câncer de mama HER-2+ no SUS

Jan 2, 2023 - Ciência & Saúde Coletiva

Batista, Joanna d'Arc Lyra; Alves, Rafael José Vargas; Cardoso, Taís Belladona; Moreno, Marcelo; Tiscoski, Katsuki Arima; Polanczyk, Carisi Anne, 2023, "Replication Data for: Efetividade do Trastuzumabe adjuvante em mulheres com câncer de mama HER-2+ no SUS", https://doi.org/10.48331/scielodata.KG1BRG, SciELO Data, V1, UNF:6:twusn2GcEJRPJRyvuyA/9g== [fileUNF]

Banco de dados do artigo.

BANCO2022_trastuz.tab

Jan 2, 2023 - Replication Data for: Efetividade do Trastuzumabe adjuvante em mulheres com câncer de mama HER-2+ no SUS

Tabular Data - 12.8 KB - 24 Variables, 90 Observations -

Add Data

Share Dataverse

Link Dataverse

Reset Modifications