Journal of Applied Oral Science

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131 to 140 of 754 Results

Figure_6 .jpg Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification JPEG Image - 111.2 KB - MD5: a264a0113bfaeea8a79565c42aabc60d Measurement of the perinuclear localization of ZOL and the positive control for macropinocytosis, dextran, in the absence and presence of 30 microM Dynasore. Violin plots display the HGF perinuclear proportion of intracellular TRITC-dextran (A) and AF647-ZOL (D) fluorescence. Hor...
Graphical_Abstract.pdf Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification Adobe PDF - 84.1 KB - MD5: 496fd3da516f74ba23d636c4a2e04675 Text summary and data displaying the major findings.
HGFIMIRescue_DataGraph.jpg Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification JPEG Image - 66.2 KB - MD5: db50edfaef672c4413910622875fe627 This graph displays the "data not shown" in the Dynasore rescue portion of Results. An optimized dose of imipramine (IMI) of 25 microM for one hour prior to 72 hours of incubation in the presence of zoledronate does not rescue the 50 microM zoledronate (ZOL)-treated HGFs. Error b...
HGFIMIRescue_PercentViabilityData.tab Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification Tabular Data - 1.9 KB - 11 Variables, 25 Observations - UNF:6:cShYK+KhoIAqGIBEkEIfQQ== This file contains the data used to make the graph that was "data not shown" in the Dynasore rescue portion of Results. The graph is the file entitled "HGFIMIRescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that an optimized dose of imipramine (IMI)...
OsteoblastPFARescue_DataGraph.jpg Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification JPEG Image - 62.9 KB - MD5: d3c779177990d91baf6a82fa93ff3a1e This graph shows that optimized doses of phosphonoformic acid (PFA) from 0.25-0.75 mM for either a one-hour pre-treatment (PRE) prior or continual exposure during 72 hours of incubation in the presence of zoledronate do not rescue the 50 microM zoledronate (ZOL)-treated human cal...
OsteoblastPFARescue_PercentViabilityData.tab Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification Tabular Data - 1.8 KB - 17 Variables, 13 Observations - UNF:6:Tt8WyaVO2OzMPxxG+C8knQ== This file contains the data used to make the graph that was part of the "data not shown" in the PFA rescue portion of Results. The graph is the file entitled "OsteoblastPFARescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that optimized doses of phosp...
OsteoclastPFARescue_DataGraph.jpg Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification JPEG Image - 61.0 KB - MD5: 67fae0c673edb167b8ee575b1ea088dc This graph shows that optimized doses of phosphonoformic acid (PFA) from 0.25-0.75 mM for either a one-hour pre-treatment (PRE) prior or continual exposure during 72 hours of incubation in the presence of zoledronate do not rescue the 50 microM zoledronate (ZOL)-treated RAW264.7,...
OsteoclastPFARescue_PercentViabilityData.tab Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification Tabular Data - 1.8 KB - 17 Variables, 14 Observations - UNF:6:fZyZ30dH8XFjiBR6clfroA== This file contains the data used to make the graph that was part of the "data not shown" in the PFA rescue portion of Results. The graph is the file entitled "OsteoclastPFARescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that optimized doses of phosp...
README.txt Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification Plain Text - 5.0 KB - MD5: d3bb043ae2b144e20f62413895983423 This file contains the dataset title, the corresponding author's name, institution, and e-mail. The data collection time span is indicated as well as a description of all the files in the dataset and how they relate to each other. A general summary of the data generation, collect...
SupplementaryDataFigure_S1.jpg Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification JPEG Image - 177.6 KB - MD5: 98ec63199d7339b808a3344a0a883871 (A) 1.2% non-denaturing agarose gel electrophoresis of purified total HGF RNA. From left to right: lane 1 – MilleniumTM RNA size marker, lane 2 – 1μg RNA, lane 3 – 2.5μg RNA. 28S rRNA and 18S rRNA band clarity with lack of degradation on the agarose gel suggests purity of the iso...

Figure_6 .jpg

Aug 30, 2024 - Replication Data for: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification

JPEG Image - 111.2 KB -

Measurement of the perinuclear localization of ZOL and the positive control for macropinocytosis, dextran, in the absence and presence of 30 microM Dynasore. Violin plots display the HGF perinuclear proportion of intracellular TRITC-dextran (A) and AF647-ZOL (D) fluorescence. Hor...

Graphical_Abstract.pdf

Adobe PDF - 84.1 KB -

Text summary and data displaying the major findings.

HGFIMIRescue_DataGraph.jpg

JPEG Image - 66.2 KB -

This graph displays the "data not shown" in the Dynasore rescue portion of Results. An optimized dose of imipramine (IMI) of 25 microM for one hour prior to 72 hours of incubation in the presence of zoledronate does not rescue the 50 microM zoledronate (ZOL)-treated HGFs. Error b...

HGFIMIRescue_PercentViabilityData.tab

Tabular Data - 1.9 KB - 11 Variables, 25 Observations -

This file contains the data used to make the graph that was "data not shown" in the Dynasore rescue portion of Results. The graph is the file entitled "HGFIMIRescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that an optimized dose of imipramine (IMI)...

OsteoblastPFARescue_DataGraph.jpg

JPEG Image - 62.9 KB -

This graph shows that optimized doses of phosphonoformic acid (PFA) from 0.25-0.75 mM for either a one-hour pre-treatment (PRE) prior or continual exposure during 72 hours of incubation in the presence of zoledronate do not rescue the 50 microM zoledronate (ZOL)-treated human cal...

OsteoblastPFARescue_PercentViabilityData.tab

Tabular Data - 1.8 KB - 17 Variables, 13 Observations -

This file contains the data used to make the graph that was part of the "data not shown" in the PFA rescue portion of Results. The graph is the file entitled "OsteoblastPFARescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that optimized doses of phosp...

OsteoclastPFARescue_DataGraph.jpg

JPEG Image - 61.0 KB -

OsteoclastPFARescue_PercentViabilityData.tab

Tabular Data - 1.8 KB - 17 Variables, 14 Observations -

This file contains the data used to make the graph that was part of the "data not shown" in the PFA rescue portion of Results. The graph is the file entitled "OsteoclastPFARescue_DataGraph.jpg" and uploaded separately in the dataset. This graph shows that optimized doses of phosp...

README.txt

Plain Text - 5.0 KB -

This file contains the dataset title, the corresponding author's name, institution, and e-mail. The data collection time span is indicated as well as a description of all the files in the dataset and how they relate to each other. A general summary of the data generation, collect...

SupplementaryDataFigure_S1.jpg

JPEG Image - 177.6 KB -

(A) 1.2% non-denaturing agarose gel electrophoresis of purified total HGF RNA. From left to right: lane 1 – MilleniumTM RNA size marker, lane 2 – 1μg RNA, lane 3 – 2.5μg RNA. 28S rRNA and 18S rRNA band clarity with lack of degradation on the agarose gel suggests purity of the iso...

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