Journal of Applied Oral Science

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111 to 120 of 754 Results

Table_S2.tab Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis Tabular Data - 3.7 KB - 11 Variables, 121 Observations - UNF:6:IrM9WIjojbbyFG6OZH/LfA== Detailed information of TMD dataset and diagnostic criteria
Table_S3.tab Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis Tabular Data - 707.0 KB - 22 Variables, 2230 Observations - UNF:6:IVH0e7BQaAHd+bHDWR4/9g== Instrumental variables used in the MR analysis
Table_S4.tab Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis Tabular Data - 3.0 KB - 10 Variables, 121 Observations - UNF:6:DnJZJX0qn3PoeSHWojPs3A== The heterogeneity of circulating inflammatory proteins instrumental variables
Table_S5.tab Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis Tabular Data - 1.8 KB - 4 Variables, 121 Observations - UNF:6:5YiDcI3d+5skP/0788ZdgA== Directional horizontal pleiotropy assessed by intercept term in MR Egger regression of the association between circulating inflammatory proteins and TMDs.
1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential Sep 30, 2024 Cazotti Pereira, Bruno; Sacramento, Catharina Marques; Sallum, Enilson Antonio; Monteiro, Mabelle de Freitas; Casarin, Renato Corrêa Viana; Casati, Marcio Zaffalon; Silvério, Karina Gonzales, 2024, "1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential", https://doi.org/10.48331/scielodata.EYNIXB, SciELO Data, V1 Periodontal dental ligament mesenchymal stem cells (PDLMSCs) play a major role in the regeneration of periodontal tissue through the neoformation of root cementum and alveolar bone. These cells are highly heterogeneous, and many present low potential to renovate the hard tissue d...
Figure_1.jpg Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential JPEG Image - 54.9 KB - MD5: 40c5d848553a5aabe8d5af740c99e723 (A) Effect of 1,25(OH)2D3 on metabolic activity. Three LOP cell populations (LOP 1, LOP 2, and LOP 3) were cultured in standard medium (CONTROL), osteogenic medium (OM), and OM + 1nM of 1,25(OH)2D3 (OM + VD), and the MTT assay for assessing cell metabolism and viability was perfo...
Figure_2.jpg Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential JPEG Image - 72.0 KB - MD5: 5127f4d23613577fd88222d860b27ea1 Real-time PCR analysis indicated a downregulation of the mRNA levels for ASPN (A), and an increased level of transcripts for BMP-2 (B) after the treatment with 1nm of 1,25(OH)2D3. (C) Correlation between BMP-2 and ASPN on day 14. Experiments were performed in triplicate three tim...
Figure_3.jpg Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential JPEG Image - 84.3 KB - MD5: 92d0fe4490bc5cf42378a3f3c0dd681b Osteoblast genes expression after 1,25(OH)2D3 treatment. Real-time PCR analysis after treatment indicated that 1,25(OH)2D3 upregulated the expression of mRNAs for RUNX2 (A), ALP (B), and OCN (C). Bars represent mean ± standard deviation (SD) where intergroup analysis statistical...
Figure_4.jpg Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential JPEG Image - 29.2 KB - MD5: a3e1d7015c7d87af5e5d65b2ebe0003e BMP-2 protein expression. Quantification of BMP-2 secreted in supernatant of LOP 1, LOP 2 and LOP 3 cells after 3, 7 and 14 days of osteogenic induction associated with 1,25(OH)2D3. Bars represent mean ± standard deviation (SD) where intergroup analysis statistical differences ar...
Figure_5.jpg Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential JPEG Image - 133.5 KB - MD5: 242b65ac7579931697e0a0ab58cc5209 Effect of 1,25(OH)2D3 on mineral nodule deposition. (A-C) Microscopic of Alizarin Red Staining (AR-S) mineralization of LOP 1, LOP 2, and LOP 3, respectively. Scale bar = 40µm. (D-F) Quantification of AR-S at 28 days. Experiments were performed in triplicate three times, with com...

Table_S2.tab

Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis

Tabular Data - 3.7 KB - 11 Variables, 121 Observations -

Detailed information of TMD dataset and diagnostic criteria

Table_S3.tab

Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis

Tabular Data - 707.0 KB - 22 Variables, 2230 Observations -

Instrumental variables used in the MR analysis

Table_S4.tab

Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis

Tabular Data - 3.0 KB - 10 Variables, 121 Observations -

The heterogeneity of circulating inflammatory proteins instrumental variables

Table_S5.tab

Nov 1, 2024 - Replication Data for: Association between circulating inflammatory proteins and temporomandibular disorders: Insight from a two-sample Mendelian randomization analysis

Tabular Data - 1.8 KB - 4 Variables, 121 Observations -

Directional horizontal pleiotropy assessed by intercept term in MR Egger regression of the association between circulating inflammatory proteins and TMDs.

1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential

Sep 30, 2024

Cazotti Pereira, Bruno; Sacramento, Catharina Marques; Sallum, Enilson Antonio; Monteiro, Mabelle de Freitas; Casarin, Renato Corrêa Viana; Casati, Marcio Zaffalon; Silvério, Karina Gonzales, 2024, "1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential", https://doi.org/10.48331/scielodata.EYNIXB, SciELO Data, V1

Periodontal dental ligament mesenchymal stem cells (PDLMSCs) play a major role in the regeneration of periodontal tissue through the neoformation of root cementum and alveolar bone. These cells are highly heterogeneous, and many present low potential to renovate the hard tissue d...

Figure_1.jpg

Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential

JPEG Image - 54.9 KB -

(A) Effect of 1,25(OH)2D3 on metabolic activity. Three LOP cell populations (LOP 1, LOP 2, and LOP 3) were cultured in standard medium (CONTROL), osteogenic medium (OM), and OM + 1nM of 1,25(OH)2D3 (OM + VD), and the MTT assay for assessing cell metabolism and viability was perfo...

Figure_2.jpg

Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential

JPEG Image - 72.0 KB -

Real-time PCR analysis indicated a downregulation of the mRNA levels for ASPN (A), and an increased level of transcripts for BMP-2 (B) after the treatment with 1nm of 1,25(OH)2D3. (C) Correlation between BMP-2 and ASPN on day 14. Experiments were performed in triplicate three tim...

Figure_3.jpg

Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential

JPEG Image - 84.3 KB -

Osteoblast genes expression after 1,25(OH)2D3 treatment. Real-time PCR analysis after treatment indicated that 1,25(OH)2D3 upregulated the expression of mRNAs for RUNX2 (A), ALP (B), and OCN (C). Bars represent mean ± standard deviation (SD) where intergroup analysis statistical...

Figure_4.jpg

Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential

JPEG Image - 29.2 KB -

BMP-2 protein expression. Quantification of BMP-2 secreted in supernatant of LOP 1, LOP 2 and LOP 3 cells after 3, 7 and 14 days of osteogenic induction associated with 1,25(OH)2D3. Bars represent mean ± standard deviation (SD) where intergroup analysis statistical differences ar...

Figure_5.jpg

Sep 30, 2024 - 1,25(OH)2D3 increases osteogenic potential of human periodontal ligament cells with low osteoblast potential

JPEG Image - 133.5 KB -

Effect of 1,25(OH)2D3 on mineral nodule deposition. (A-C) Microscopic of Alizarin Red Staining (AR-S) mineralization of LOP 1, LOP 2, and LOP 3, respectively. Scale bar = 40µm. (D-F) Quantification of AR-S at 28 days. Experiments were performed in triplicate three times, with com...

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