Journal of Applied Oral Science

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31 to 39 of 39 Results

A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants Feb 2, 2023 Ren, Jiabao; Zhao, Ya; Yuan, Yunyun; Zhang, Jing; Ding, Yulin; Li, Meikang; An, Yilin; Chen, Wenjing; Zhang, Li; Liu, Boyu; Zheng, Shushen; Shen, Wenjing, 2023, "A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants", https://doi.org/10.48331/scielodata.OMMQEH, SciELO Data, V1 It has been reported that >91.9% of non-syndromic tooth agenesis cases are caused by seven pathogenic genes. Objective: Here, we report novel heterozygous PAX9 variants in a Chinese family with non-syndromic oligodontia and summarize the reported genotype-phenotype relationship o...
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways Jan 2, 2023 Chen, Yan; Liu, Yang; Li, Hao; Huna, Risu; Tan, Xiaohan; Li, Ning; Zhang, Yiying; Jiao, Xiaohui; Liu, Mingyue, 2023, "C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways", https://doi.org/10.48331/scielodata.XR5TEV, SciELO Data, V1 Objective: Abnormal complement activation is associated with periodontitis. W54011 is a novel non-peptide C5aR antagonist (C5aRA) that exhibits favorable anti-inflammatory effects in various inflammatory models. However, whether W54011 inhibits periodontitis has not yet been full...
Microarray and bioinformatic analysis of conventional ameloblastoma Dec 20, 2022 Jacinto-Alemán, Luis Fernando; Portilla-Robertson, Javier; Leyva-Huerta, Elba Rosa; Ramírez-Jarquín, Josué Orlando; Villanueva-Sánchez, Francisco Germán, 2022, "Microarray and bioinformatic analysis of conventional ameloblastoma", https://doi.org/10.48331/scielodata.Z2S8X9, SciELO Data, V1 Ameloblastoma is a highly aggressive odontogenic tumor, and its pathogenesis is associated with multiple participating genes. Objective: Our aim was to identify and validate new critical genes of conventional ameloblastoma using microarray and bioinformatics analysis. Methods: Ge...
The effect of BMP9 on inflammation in the early stage of pulpitis Dec 19, 2022 Song, Tianzhu; Li, Xiangfen; Liu, Liu; Zeng, Yanglin; Song, Dongzhe; Huang, Dingming, 2022, "The effect of BMP9 on inflammation in the early stage of pulpitis", https://doi.org/10.48331/scielodata.902G8X, SciELO Data, V1, UNF:6:V/vDFTp1ngufPZY0vbdIxw== [fileUNF] Bone morphogenetic protein 9 (BMP9) might be associated with inflammatory responses to different diseases, but its relationship with pulpitis is unknown. Objective: The purpose of this study was to explore the effects and mechanism of BMP9 in pulpitis. Methodology: A rat pulpitis...
The impact of the COVID-19 pandemic on dental trauma attendance: Dec 13, 2022 Campos, Débora e Silva; Muniz, Isis de Araújo Ferreira; Gomes, Amanda Gomes; Beserra, Letícia Regina Marques; Santos, Luyra Elyka Daniel dos; Batista, André Ulisses Dantas; Gominho, Luciana Ferraz; Salazar-Silva, Juan Ramon; D’Assunção, Fábio Luiz Cunha, 2022, "The impact of the COVID-19 pandemic on dental trauma attendance:", https://doi.org/10.48331/scielodata.78SHP1, SciELO Data, V1, UNF:6:nqDLQpR3hBnrrqvgJtsYZA== [fileUNF] The purpose of this systematic review and meta-analysis was to analyze the impact of the COVID-19 pandemic on dental trauma patient attendance. This study was registered in the PROSPERO system, using the CRD42021288398 protocol. Searches were performed in PubMed, Scopus, Web of S...
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur Dec 12, 2022 Tou, Gabriel Antônio dos Anjos; Gomes, José Messias; Rinco, Luiza Santana de Oliveira; Yamauti, Mônica; Diniz, Ivana Márcia Alves; Pires, Fabiane; Schmidt, Marcella Emilia Petra; Menezes, Helvécio Costa; Cardeal, Zenilda de Lourdes; Bottoli, Carla Beatriz Grespan; Macari, Soraia, 2022, "Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur", https://doi.org/10.48331/scielodata.7YDW7I, SciELO Data, V1, UNF:6:jXZZS2trP0g2dpOMzBcQ6A== [fileUNF] The data is related to the evaluation of the release of bisphenol-A glycidyl methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA), bisphenol A (BPA), and phthalates of the composite resin used in the bonding of spurs applied in the treatment of children with anterior...
Periodontal disease severity is associated to pathogenic consortia comprising putative and candidate periodontal pathogens Nov 29, 2022 Araújo, Lélia Lima; Lourenço, Talita Gomes Baêta; Colombo, Ana Paula Vieira, 2022, "Periodontal disease severity is associated to pathogenic consortia comprising putative and candidate periodontal pathogens", https://doi.org/10.48331/scielodata.ZYQXJH, SciELO Data, V1, UNF:6:QcPYieOFHZOLfvyxa/+fiw== [fileUNF] Background: Complex interactions among distinct oral taxa within a dysbiotic periodontal microenvironment are not fully understood. Hypothesis/ gap statement: Based on a holistic concept of polymicrobial etiology, we hypothesized that putative and novel periodontal pathogens are...
Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice Nov 4, 2022 Chaves, Ian; Zicker, Marina Campos; Laranjeira, Alice de Oliveira; Silveira, Ana Letícia Malheiros; Aguiar, Daniele Cristina de; Barrioni, Breno Rocha; Ferreira, Adaliene Versiani de Matos; Teixeira, Mauro Martins; Silva, Tarcília Aparecida da; Souza, Daniele da Glória de; Madeira, Mila Fernandes Moreira, 2022, "Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice", https://doi.org/10.48331/scielodata.OIBYC1, SciELO Data, V1 The current study aimed to relate obesity, changes in oral microbiota, and induction of alveolar bone loss, as seen in PD. Two obesity mice models were performed, one using 12 weeks of the dietary protocol with a high-fat (HF) diet in C57BL/6 mice and the other using leptin recep...
Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis Nov 3, 2022 Chen, Xuan; Dou, Jinge; Fu, Zhuohui; Qiu, Yang; Zou, Ling; Huang, Dingming; Tan, Xuelian, 2022, "Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis", https://doi.org/10.48331/scielodata.UNJC4K, SciELO Data, V1, UNF:6:XYVn3HLR+CX4EJfvpKpN9w== [fileUNF] Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated by Porphyromonas gingivalis. Methodology: Macrophage polarization, IL-6/STAT3 expression, and the p...

A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants

Feb 2, 2023

Ren, Jiabao; Zhao, Ya; Yuan, Yunyun; Zhang, Jing; Ding, Yulin; Li, Meikang; An, Yilin; Chen, Wenjing; Zhang, Li; Liu, Boyu; Zheng, Shushen; Shen, Wenjing, 2023, "A novel PAX9 compound heterozygous variant in a Chinese family with non-syndromic oligodontia and genotype-phenotype analysis of PAX9 variants", https://doi.org/10.48331/scielodata.OMMQEH, SciELO Data, V1

It has been reported that >91.9% of non-syndromic tooth agenesis cases are caused by seven pathogenic genes. Objective: Here, we report novel heterozygous PAX9 variants in a Chinese family with non-syndromic oligodontia and summarize the reported genotype-phenotype relationship o...

C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

Jan 2, 2023

Chen, Yan; Liu, Yang; Li, Hao; Huna, Risu; Tan, Xiaohan; Li, Ning; Zhang, Yiying; Jiao, Xiaohui; Liu, Mingyue, 2023, "C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways", https://doi.org/10.48331/scielodata.XR5TEV, SciELO Data, V1

Objective: Abnormal complement activation is associated with periodontitis. W54011 is a novel non-peptide C5aR antagonist (C5aRA) that exhibits favorable anti-inflammatory effects in various inflammatory models. However, whether W54011 inhibits periodontitis has not yet been full...

Microarray and bioinformatic analysis of conventional ameloblastoma

Dec 20, 2022

Jacinto-Alemán, Luis Fernando; Portilla-Robertson, Javier; Leyva-Huerta, Elba Rosa; Ramírez-Jarquín, Josué Orlando; Villanueva-Sánchez, Francisco Germán, 2022, "Microarray and bioinformatic analysis of conventional ameloblastoma", https://doi.org/10.48331/scielodata.Z2S8X9, SciELO Data, V1

Ameloblastoma is a highly aggressive odontogenic tumor, and its pathogenesis is associated with multiple participating genes. Objective: Our aim was to identify and validate new critical genes of conventional ameloblastoma using microarray and bioinformatics analysis. Methods: Ge...

The effect of BMP9 on inflammation in the early stage of pulpitis

Dec 19, 2022

Song, Tianzhu; Li, Xiangfen; Liu, Liu; Zeng, Yanglin; Song, Dongzhe; Huang, Dingming, 2022, "The effect of BMP9 on inflammation in the early stage of pulpitis", https://doi.org/10.48331/scielodata.902G8X, SciELO Data, V1, UNF:6:V/vDFTp1ngufPZY0vbdIxw== [fileUNF]

Bone morphogenetic protein 9 (BMP9) might be associated with inflammatory responses to different diseases, but its relationship with pulpitis is unknown. Objective: The purpose of this study was to explore the effects and mechanism of BMP9 in pulpitis. Methodology: A rat pulpitis...

The impact of the COVID-19 pandemic on dental trauma attendance:

Dec 13, 2022

Campos, Débora e Silva; Muniz, Isis de Araújo Ferreira; Gomes, Amanda Gomes; Beserra, Letícia Regina Marques; Santos, Luyra Elyka Daniel dos; Batista, André Ulisses Dantas; Gominho, Luciana Ferraz; Salazar-Silva, Juan Ramon; D’Assunção, Fábio Luiz Cunha, 2022, "The impact of the COVID-19 pandemic on dental trauma attendance:", https://doi.org/10.48331/scielodata.78SHP1, SciELO Data, V1, UNF:6:nqDLQpR3hBnrrqvgJtsYZA== [fileUNF]

The purpose of this systematic review and meta-analysis was to analyze the impact of the COVID-19 pandemic on dental trauma patient attendance. This study was registered in the PROSPERO system, using the CRD42021288398 protocol. Searches were performed in PubMed, Scopus, Web of S...

Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur

Dec 12, 2022

Tou, Gabriel Antônio dos Anjos; Gomes, José Messias; Rinco, Luiza Santana de Oliveira; Yamauti, Mônica; Diniz, Ivana Márcia Alves; Pires, Fabiane; Schmidt, Marcella Emilia Petra; Menezes, Helvécio Costa; Cardeal, Zenilda de Lourdes; Bottoli, Carla Beatriz Grespan; Macari, Soraia, 2022, "Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur", https://doi.org/10.48331/scielodata.7YDW7I, SciELO Data, V1, UNF:6:jXZZS2trP0g2dpOMzBcQ6A== [fileUNF]

The data is related to the evaluation of the release of bisphenol-A glycidyl methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA), bisphenol A (BPA), and phthalates of the composite resin used in the bonding of spurs applied in the treatment of children with anterior...

Periodontal disease severity is associated to pathogenic consortia comprising putative and candidate periodontal pathogens

Nov 29, 2022

Araújo, Lélia Lima; Lourenço, Talita Gomes Baêta; Colombo, Ana Paula Vieira, 2022, "Periodontal disease severity is associated to pathogenic consortia comprising putative and candidate periodontal pathogens", https://doi.org/10.48331/scielodata.ZYQXJH, SciELO Data, V1, UNF:6:QcPYieOFHZOLfvyxa/+fiw== [fileUNF]

Background: Complex interactions among distinct oral taxa within a dysbiotic periodontal microenvironment are not fully understood. Hypothesis/ gap statement: Based on a holistic concept of polymicrobial etiology, we hypothesized that putative and novel periodontal pathogens are...

Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice

Nov 4, 2022

Chaves, Ian; Zicker, Marina Campos; Laranjeira, Alice de Oliveira; Silveira, Ana Letícia Malheiros; Aguiar, Daniele Cristina de; Barrioni, Breno Rocha; Ferreira, Adaliene Versiani de Matos; Teixeira, Mauro Martins; Silva, Tarcília Aparecida da; Souza, Daniele da Glória de; Madeira, Mila Fernandes Moreira, 2022, "Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice", https://doi.org/10.48331/scielodata.OIBYC1, SciELO Data, V1

The current study aimed to relate obesity, changes in oral microbiota, and induction of alveolar bone loss, as seen in PD. Two obesity mice models were performed, one using 12 weeks of the dietary protocol with a high-fat (HF) diet in C57BL/6 mice and the other using leptin recep...

Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis

Nov 3, 2022

Chen, Xuan; Dou, Jinge; Fu, Zhuohui; Qiu, Yang; Zou, Ling; Huang, Dingming; Tan, Xuelian, 2022, "Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis", https://doi.org/10.48331/scielodata.UNJC4K, SciELO Data, V1, UNF:6:XYVn3HLR+CX4EJfvpKpN9w== [fileUNF]

Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated by Porphyromonas gingivalis. Methodology: Macrophage polarization, IL-6/STAT3 expression, and the p...

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