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Unknown - 226.3 KB -
MD5: 58f73bf295f689869841592d5b27b145
Sanger sequencing result of the proband's little sister of PAX9 exon4(NM_001372076.1). |
Unknown - 237.7 KB -
MD5: 34861b4716f5359c8af9980dfe1435d2
Sanger sequencing result of the proband's mother of PAX9 exon2(NM_001372076.1). |
Unknown - 223.2 KB -
MD5: 5315d5da6dac2e000a09fd957cc542b3
Sanger sequencing result of the proband's mother of PAX9 exon4(NM_001372076.1). |
JPEG Image - 201.8 KB -
MD5: 465e7252fd717d9a5159f87cb558f207
Proband-s sister(III-2) |
MS Excel Spreadsheet - 92.0 KB -
MD5: 22b8c2fe80952edb3035d4688427be40
PAX9 mutation genotypes and phenotypes |
Jan 2, 2023 -
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways
MS Excel Spreadsheet - 22.0 KB -
MD5: ec22d187f03e00ade73c21297cd9e7c9
Figure 1. Primers sequences used for RT-PCR and RT-qPCR. |
Jan 2, 2023 -
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways
JPEG Image - 4.6 MB -
MD5: eed36ac30a4f1843c5fa4336ab68af16
Figure 2. Isolation and culture of human gingival fibroblasts (HGFs).(A) The appearance of primary HGFs cultured for 2 days.(B) The appearance of primary HGFs cultured for 4 days.(C) The appearance of primary HGFs cultured for 7 days.(D) The appearance of primary HGFs cultured fo... |
Jan 2, 2023 -
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways
JPEG Image - 5.9 MB -
MD5: de0869fde45f658ac92b5c4ce00aeb92
Figure 3. Identification of the 2th passage cells from HGFs with immunofluorescent staining.(A-C) The green positive expression of FSP-1 in the cytoplasmof HGFs.(D-F) Keratin is unstained in the cytoplasm.(G-I) The positive staining of vimentin in the cytoplasm of HGFs was red fl... |
Jan 2, 2023 -
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways
JPEG Image - 975.3 KB -
MD5: 46329664c6f49b2e3d5b260470318045
Figure 4. The content of C5a in the cell supernatant of the different group was measured by ELISA assay. Data represent the mean ± SEM. of three independent experiments. +P < 0.05 vs. the control group. *P < 0.05 vs. the LPS+C5aRA group. |
Jan 2, 2023 -
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways
JPEG Image - 936.2 KB -
MD5: 5a247c4226aa3dcdf08872097e0104dc
Figure 5. Effects of C5aR antagonists on the expression of C5aR and inflammatory factors of LPS-induced HGFs by RT-qPCR and Western blotting.(A) C5aRA inhibited expression of C5aR, TNF-α, IL-1β, and IL-6 mRNA in LPS-stimulated HGFs. (B) C5aR antagonists inhibited expression of C5... |