Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro

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Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro
Baumann, Tommy; Niemeyer, Samira Helena; Lussi, Adrian; Scaramucci, Taís; Carvalho, Thiago Saads, 2023, "Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro", https://doi.org/10.48331/scielodata.ZTZ1PM, SciELO Data, V1, UNF:6:kN2Ni7IJmjI1gvMYgYTavA== [fileUNF]
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Description
Polyphenols interact with salivary proteins and can thereby improve the erosion protective properties of the pellicle. This effect could be exploited to create rinsing solutions with polyphenols as active ingredients for erosion prevention. Such rinses would, other than the current gold standard for erosion protective rinsing solutions, not rely on stannous ions. This would offer alternatives for patients with concerns regarding the composition of rinsing solutions and preferring bio-products. The objective was to develop an erosion-preventive rinsing solution containing natural polyphenol-rich extracts. We prepared solutions containing polyphenols from either grapeseed extract or cranberry extract, added 500 ppm fluoride, and additionally flavors and sweeteners. Controls were deionized water, 500 ppm fluoride solution, and the gold standard rinse in the field (containing Sn2+/F-). Enamel specimens (n = 15/group) were subjected to 5 cycles of: salivary pellicle formation, modification with the solutions, further salivary pellicle formation, and erosive challenge. Surface microhardness, surface reflection intensity, and amount of calcium release were measured. Surface microhardness and surface reflection intensity were then ransformed to relative surface microhardness and relative surface reflection intensity. Data were analysed with Kruskal-Wallis and Wilcoxon rank sum tests (α = 0.05). (2023-06-23)
Subject Medicine, Health and Life Sciences
Keyword Hardness, Surface Properties, Calcium, Dental pellicle, Tooth Erosion, Polyphenols
Related Publication Baumann T, Niemeyer SH, Lussi A, Scaramucci T, Carvalho TS. Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro. J Appl Oral Sci. 2023;31:e20230108. doi: 10.1590/1678-7757-2023-0108 doi: 10.1590/1678-7757-2023-0108
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data_analysis_rinses_extracts.txt
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excerpt of "data_rinses_extracts.txt" containing all the data that was statistically analysed
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data_pre_tests_rinses_extracts.txt
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MD5: 9ad1507f043a0d270d50bf6d0751402e
all the data for the supplemental material to the publication "Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro"
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data_rinses_extracts.txt
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all the data for the main article "Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro"
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Figure_1.tab
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6 Variables, 13 Observations UNF:6:kN2Ni7IJmjI1gvMYgYTavA==
Experimental groups and their compositions. * Fairvital B.V., Germany. Content of OPC in extract: 95%; ¤ BioProphyl® GmbH (Urocyan), Germany. Content of PAC in extract: 6%; † elmex® erosion
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Figure_2.jpg
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Published Jun 23, 2023
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MD5: de737de5ba2f79f7712e21cac6d4d8a2
Relative surface microhardness (%) after all cycles. Different letters indicate significant differences (p < 0.05).
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Relative surface reflection intensity (%) after all cycles, before pellicle removal. Different letters indicate significant differences (p < 0.05).
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Relative surface reflection intensity (%) after all cycles, after pellicle removal. Different letters indicate significant differences (p < 0.05).
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MD5: 40a75c53b593c36fed368b9af3ecb757
Total amount of calcium released to the citric acid. Different letters indicate significant differences (p < 0.05).
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README.txt
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